• Product NameNeopentyl glycol
  • CasNo. 126-30-7
  • MFC5H12O2
  • MW104.149
  • Purity
  • Appearancewhite crystalline solid
  • Packing
  • Contact usInquiry

Product Details

CasNo: 126-30-7

MF: C5H12O2

Appearance: white crystalline solid

Quality Factory Supply Neopentyl glycol 126-30-7 Cheapest Price

  • Molecular Formula:C5H12O2
  • Molecular Weight:104.149
  • Appearance/Colour:white crystalline solid 
  • Vapor Pressure:<0.8 mm Hg ( 20 °C) 
  • Melting Point:126-128°C 
  • Refractive Index:1.443 
  • Boiling Point:209.8 °C at 760 mmHg 
  • PKA:14.57±0.10(Predicted) 
  • Flash Point:107.2 °C 
  • PSA:40.46000 
  • Density:0.981 g/cm3 
  • LogP:-0.00280 

2,2-Dimethyl-1,3-propanediol(Cas 126-30-7) Usage

Chemical Structure

The chemical formula for Neopentyl glycol (NPG) is C5H12O2, and it is a propane-1,3-diol carrying two methyl groups at position 2.Neopentyl glycol is soluble in water, benzene, chloroform, and very soluble in ethanol and diethyl ether. Neopentylglycol (NPG) is a unique polyalcohol offering superior performance advantages in many end-use applications due to its high chemical and thermal stability. It is a unique diol offering superior performance advantages in many end-use applications. These advantages are derived from its chemical structure. The location of the hydroxyl groups on primary carbon atoms allows rapid esterification. Additionally, the two methyl groups, instead of the usual two hydrogen atoms, on the alpha carbon atom are responsible for the high chemical and thermal stability of Neopentylglycol and its derivatives.

Application

Neopentyl glycol is used in the synthesis of polyesters, paints, lubricants, and plasticizers. When used in the manufacture of polyesters, it enhances the stability of the product towards heat, light, and water. By esterification reaction with fatty or carboxylic acids, synthetic lubricating esters with reduced potential for oxidation or hydrolysis, compared to natural esters, can be produced. NPG is used primarily in base resins for coatings. In powder coating formulations, Neopentylglycol offers the additional advantage of providing small differences between the glass transition temperature and melting point. Important areas of application include general metal, appliance, metal furniture, automotive and machinery coatings. Important uses are also found in hydraulic fluids, synthetic lubricant oils, greases, metalworking fluids and aircraft engine lubricants. Other outlets include textiles, pharmaceuticals, pesticides, plasticizers and petroleum. High quality NPG is shipped as flake, molten and slurry. The high-quality NPG is the component in polyester resins for industrial coatings and fiberglass-reinforced plastics applications, and most polyester resin formulations contain NPG as the sole glycol component, or it is used in conjunction with a modifying glycol to achieve desired properties. NPG is also used in polyester polyols for polyurethane coatings for the automotive, industrial maintenance, transportation, and aerospace markets.

Chemical Properties

white solid

Uses

NPG Glycol is used in the synthesis of tetraphenylporphyrins. Also used in the synthesis of Bryostatin 2, a protein kinase modulator.

General Description

White crystalline solid. Melting point 130°C.

Air & Water Reactions

Soluble in water.

Reactivity Profile

2,2-Dimethyl-1,3-propanediol may generate toxic gases in combination of with alkali metals, nitrides, and strong reducing agents. Reacts with inorganic acids and carboxylic acids to form esters plus water. Converted to aldehydes or acids by oxidizing agents. May initiate the polymerization of isocyanates and epoxides.

Health Hazard

May be harmful by ingestion or skin absorption. Causes eye and skin irritation. Material is irritating to mucous membrane and upper respiratory tract. INHALATION: Call for medical aid. Remove to fresh air. If breathing has stopped, give artificial respiration. If breathing is difficult, give oxygen.

Fire Hazard

Special Hazards of Combustion Products: Emits toxic fumes under fire condition.

Flammability and Explosibility

Nonflammable

Purification Methods

Crystallise the diol from *benzene or acetone/water (1:1). [Beilstein 1 IV 2551.]

InChI:InChI=1/C5H12O2/c1-2-5(3-6)4-7/h5-7H,2-4H2,1H3

126-30-7 Relevant articles

-

Nikoletic,M. et al.

, p. 649 - 660 (1967)

-

Alkylating potential of oxetanes

Gomez-Bombarelli, Rafael,Palma, Bernardo Brito,Martins, Celia,Kranendonk, Michel,Rodrigues, Antonio S.,Calle, Emilio,Rueff, Jose,Casado, Julio

, p. 1275 - 1281 (2010)

Small, highly strained heterocycles are ...

A strategy for generating alkyl radicals from aliphatic esters and lactones via sequential hydrolysis and photoinduced decarboxylation

Saito, Hikaru,Kanetake, Takayuki,Osaka, Kazuyuki,Maeda, Kousuke,Morita, Toshio,Yoshimi, Yasuharu

, p. 1645 - 1648 (2015)

Sequential hydrolysis and photoinduced d...

-

Boehm

, p. 955 (1906)

-

-

Apel,Tollens

, (1896)

-

Identification and Counting of Carbonyl and Hydroxyl Functionalities in Protonated Bifunctional Analytes by Using Solution Derivatization Prior to Mass Spectrometric Analysis Via Ion-Molecule Reactions

Somuramasami, Jayalakshmi,Winger, Brian E.,Gillespie, Todd A.,Kenttaemaa, Hilkka I.

, p. 773 - 784 (2010)

A mass spectrometric method has been dev...

-

Campbell,Rydon

, p. 3002,3005 (1953)

-

An Efficient Deprotection of 2,6-Bis(trifluoromethyl)phenylboronic Esters via Catalytic Protodeboronation Using Tetrabutyl ammonium Fluoride

Makino, Kazuishi,Nojima, Shinya,Shimada, Naoyuki,Urata, Sari

, p. 2300 - 2304 (2019)

We herein describe an efficient deprotec...

-

Wessely

, p. 66 (1901)

-

Method for producing a shaped catalyst body

-

Page/Page column 29-32, (2021/11/19)

Provided herein is a novel process for p...

Preparation method of hydroxypivalaldehyde and application of hydroxypivalaldehyde in preparation of neopentyl glycol

-

Paragraph 0039; 0042-0044; 0047-0049; 0052-0053, (2021/02/09)

The invention provides a preparation met...

Protodeboronation of (Hetero)Arylboronic Esters: Direct versus Prehydrolytic Pathways and Self-/Auto-Catalysis

Hayes, Hannah L. D.,Wei, Ran,Assante, Michele,Geogheghan, Katherine J.,Jin, Na,Tomasi, Simone,Noonan, Gary,Leach, Andrew G.,Lloyd-Jones, Guy C.

supporting information, p. 14814 - 14826 (2021/09/13)

The kinetics and mechanism of the base-c...

Photo-Induced ortho-C-H Borylation of Arenes through in Situ Generation of Rhodium(II) Ate Complexes

Araujo Dias, Ant?nio Junio,Nagashima, Yuki,Tanaka, Jin,Tanaka, Ken

supporting information, p. 11325 - 11331 (2021/08/03)

Photoinduced in situ "oxidation"of half-...

126-30-7 Process route

5,5-dimethyl-2-(1-morpholino-1-phenylethyl)-2-oxo-1,3,2-dioxaphosphorinane
136001-43-9

5,5-dimethyl-2-(1-morpholino-1-phenylethyl)-2-oxo-1,3,2-dioxaphosphorinane

morpholin hydrochloride
10024-89-2

morpholin hydrochloride

2,2-Dimethyl-1,3-propanediol
126-30-7

2,2-Dimethyl-1,3-propanediol

acetophenone
98-86-2

acetophenone

Conditions
Conditions Yield
With hydrogenchloride; water; In benzene; also in dioxane;
 
1-(2,2-dimethyl-3-hydroxypropoxy)-2,4-dinitronaphthalene
79309-08-3

1-(2,2-dimethyl-3-hydroxypropoxy)-2,4-dinitronaphthalene

2,4-dinitro-[1]naphthol; sodium-(2.4-dinitro-naphtholate-<sup>(1)</sup>)
887-79-6

2,4-dinitro-[1]naphthol; sodium-(2.4-dinitro-naphtholate-(1))

2,2-Dimethyl-1,3-propanediol
126-30-7

2,2-Dimethyl-1,3-propanediol

Conditions
Conditions Yield
With sodium hydroxide; In water; at 25 ℃; Rate constant; different concentations of NaOH;
 

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