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CasNo: 7004-03-7
MF: C5H11NO2
Description |
Valine is an essential α-amino acid that plays a vital role in protein biosynthesis. Structurally, it contains an α-amino group, an α-carboxylic acid group, and a side chain comprised of an isopropyl group, which renders it a non-polar aliphatic amino acid. |
Uses |
Valine is integral to the process of protein synthesis, where it serves as one of the building blocks for the construction of proteins. During translation, ribosomes utilize messenger RNA (mRNA) templates to assemble amino acids, including valine, into polypeptide chains according to the genetic code. Branched-chain amino acids, including valine, are utilized by the body as substrates for energy production. During periods of increased energy demand, such as exercise or metabolic stress, valine can be oxidized in skeletal muscle to generate ATP, the primary energy currency of the cell. |
Synthesis |
Valine can be synthesized by hydrolysis of aminoisobutyronitrile which is obtained by amination and cyanation of aminoisoaldehyde. |
Who Evaluation |
Evaluation year: 2004 |
InChI:InChI:1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)
The fungal strain Fusarium graminearum F...
More than 20% of the valine in cellular proteins from such an editing mutant organism could be replaced with the noncanonical aminobutyrate, sterically similar to cysteine. Thus, the editing function may have played a central role in restricting the genetic code to 20 amino acids.
Surfactins are natural biosurfactants wi...
C28H41N5O10
L-alanin
L-valine
(2R)-aspartic acid
Conditions | Yield |
---|---|
With hydrogenchloride; water; at 120 ℃; for 14h;
|
amantamide
L-valine
L-leucine
L-isoleucine
N-methyl-L-leucine
N-methyl-D-phenylalanine
glycine
(-)-α-methylamino-β-methylbutyric acid
L-proline
Conditions | Yield |
---|---|
With hydrogenchloride; In water; at 110 ℃; for 24h;
|
4-isopropylidene-2-thioxo-thiazolidin-5-one
2-chloro-3-methylbutanoic acid
2-bromoisovaleric acid
2-isopropyl-malonamic acid
(+/-)-N-(2-Thenyl)valin
N-(2-chloro-hexanoyl)-valine
N-[(2,4,5-trichloro-phenoxy)-acetyl]-DL-valine
N-(N-benzoyl-glycyl)-valine