• Product NameIsoflavone
  • CasNo. 574-12-9
  • MFC15H10O2
  • MW222.243
  • Purity
  • Appearance
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Product Details

CasNo: 574-12-9

MF: C15H10O2

Factory Supply High Purity Isoflavone 574-12-9,Offer 574-12-9 Customized Supply

  • Molecular Formula:C15H10O2
  • Molecular Weight:222.243
  • Vapor Pressure:1.41E-05mmHg at 25°C 
  • Melting Point:150oC 
  • Refractive Index:1.635 
  • Boiling Point:367 °C at 760 mmHg 
  • Flash Point:171.1 °C 
  • PSA:30.21000 
  • Density:1.239 g/cm3 
  • LogP:3.46000 

Isoflavone(Cas 574-12-9) Usage

Main effects

Isoflavones are non-nutritive botanical compounds that are rich in soy products and a few other plant species; both genistein and ?glycetein are isoflavones. Their chemical structure looks similar to estrone (also known as estrogen), a steroid hormone. Plant sources: produced mainly from soybeans, lentils, pod legumes s well as highly processed food made from soybeans such as vegetarian meat, soybean flour, tofu and soy milk. Among them, tofu retains more of isoflavone content than milk. Main functions of isoflavones: Reduce LDL cholesterol, help to prevent or cure menopausal syndromes and provide the linoleic acid and linoloinic acid needed by human body. Balance blood cholesterol and reduce blood cholesterol levels. Make arteries more flexible and prevent damage to heart Enhance bone density, reduce calcium loss and reduce the chance of suffering from osteoporosis. Reduce the chance of suffering from cancer, especially breast cancer and prostate cancer. Relieve menopause discomfort, such as hot flash, fever, emotional instability, headache, insomnia, fatigue, night sweats, vaginal dryness and so on. Treat Enteritis syndrome, hot flash, osteoporosis, cardiovascular disease and cancer, also help fight coronary heart disease. Flavonoids can reduce the formation of free radicals and help regeneration of other antioxidants. Soy isoflavones are a type of natural plant estrogen which is good to human body. The plant bioactive element extracted from natural soybeans is very similar to the estrogen molecular structure and can be combined with female estrogen receptors and play two-ways regulation on estrogen safely and with no side effects, so it is also known as "phytoestrogen." It can relieve osteoporosis and other symptoms caused by menopause, delay skin aging, improve skin quality, make female skin smooth, delicate and elastic. Due to its role in improvement of women life quality, it is also called "feminine charm factor".

Isomers of flavonoids

Isoflavones are isomers of flavones with some physiological activity.The phenyl group side chain of its γ-pyrazone ring is not connected to C2 position but to C3 position. Natural isoflavones are mainly found in angiosperms and some members of the Fabaceae Rosaceae and Iridaceae family. The kudzu root, one of the legume contains five isoflavone derivatives, namely, glycinin, daidzein, puerarin, puerarin- 7-xyloside and daidzein-4 ', 7-diglucoside. The structure of isoflavones compound are similar to that of estrogen, so generally it is regarded as the precursor substances of hormone, and it differs from flavonoids compound in its negative reaction against hydrochloric acid and magnesium powder.

Uses

Antioxygenation, estrogen-like, cancer prevention and anti-cancer, disease prevention such as senile dementia, cardiovascular diseases and breast cancer, improvement of life quality.

Definition

ChEBI: A simplest member of the class of isoflavones that is 4H-chromen-4-one in which the hydrogen at position 3 is replaced by a phenyl group.

InChI:InChI=1/C15H10O2/c16-15-12-8-4-5-9-14(12)17-10-13(15)11-6-2-1-3-7-11/h1-10H

574-12-9 Relevant articles

Rhodium complexes catalyze oxidative coupling between salicylaldehyde and phenylacetylene via C-H bond activation

Jia, Hongge,Tang, Yanan,Shi, Yongqiang,Ma, Liqun,He, Zijian,Lai, Weiwei,Yang, Yi,Wang, Yazhen,Zang, Yu,Xu, Shuangping

, p. 1791 - 1795 (2017)

A coupling reaction between salicylaldeh...

Identification of ortho catechol-containing isoflavone as a privileged scaffold that directly prevents the aggregation of both amyloid β plaques and tau-mediated neurofibrillary tangles and its in vivo evaluation

Do, Ji Min,Gee, Min Sung,Inn, Kyung-Soo,Kim, Jong-Ho,Kim, Nam Kwon,Kim, Nam-Jung,Lee, Hyun Woo,Lee, Jong Kil,Seo, Min-Duk,Seong, Ji Hye,Son, Seung Hwan,Yoo, Hyung-Seok,Yoo, Ji-Na

, (2021/07/01)

In this study, polyhydroxyisoflavones th...

Stille coupling for the synthesis of isoflavones by a reusable palladium catalyst in water

Chang, Ya-Ting,Liu, Ling-Jun,Peng, Wen-Sheng,Lin, Lin-Ting,Chan, Yi-Tsu,Tsai, Fu-Yu

, p. 469 - 475 (2021/02/03)

Isoflavones were synthesized from the re...

Ionic liquids and ohmic heating in combination for Pd-catalyzed cross-coupling reactions: Sustainable synthesis of flavonoids

Silva, Artur M. S.,Silva, Vera L. M.,Soengas, Raquel G.

, (2020/04/09)

In order to meet the increasing demand f...

The oxidative coupling between benzaldehyde derivatives and phenylacetylene catalyzed by rhodium complexes via C-H bond activation

Jia, Hongge,Ma, Liqun,Shi, Yongqiang,Song, Heming,Tang, Yanan,Wang, Qingji,Wang, Yazhen,Xu, Shuangping,Yang, Guoxing,Zang, Yu,Zhao, Xinyi

, p. 20 - 25 (2020/03/30)

This paper reports the use of rhodium (R...

574-12-9 Process route

3-bromo-4H-chromen-4-one
49619-82-1

3-bromo-4H-chromen-4-one

phenylboronic acid
98-80-6

phenylboronic acid

isoflavone
574-12-9

isoflavone

Conditions
Conditions Yield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0); In water; benzene; for 6h; Heating;
94%
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; In benzene; for 53h; Reflux; Inert atmosphere;
94%
With potassium carbonate; (1-benzothiazol-2-yl-ethanone oxime)dichloropalladium(II); In toluene; at 150 ℃; for 0.133333h; microwave irradiation;
93%
With tetrabutylammomium bromide; sodium carbonate; In water; at 100 ℃; for 1h; Solvent; Concentration; Green chemistry;
93%
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; potassium carbonate; In water; N,N-dimethyl-formamide; at 90 ℃; Inert atmosphere;
86%
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0); In water; benzene; for 6h; Product distribution; Heating; other bases and reaction time;
 
With potassium carbonate; trans-[PdCl2(2-ethyl-2-oxazoline-κ1N)2]; In toluene; for 24h; Heating;
 
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; In toluene; Inert atmosphere; Reflux;
 
salicylaldehyde
90-02-8

salicylaldehyde

α-bromoacetophenone
70-11-1

α-bromoacetophenone

isoflavone
574-12-9

isoflavone

Conditions
Conditions Yield
α-bromoacetophenone; With thiamine hydrochloride; In ethanol; at 20 ℃; for 0.25h; Green chemistry;
salicylaldehyde; In ethanol; at 20 ℃; for 1h; Solvent; Time; Reagent/catalyst; Green chemistry;
88%

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