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CasNo: 52705-93-8
MF: C48H82O18
Description |
Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Notably, ginsenoside Rd is converted to other ginsenosides in response to steaming or heating plant materials, leading to loss of these activities. |
Uses |
Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia. |
InChI:InChI=1/C48H82O18/c1-21(2)15-22(3)17-48(8,66-43-40(60)37(57)34(54)28(19-50)62-43)24-11-13-47(7)23-9-10-30-45(4,5)31(12-14-46(30,6)25(23)16-26(52)32(24)47)64-44-41(38(58)35(55)29(20-51)63-44)65-42-39(59)36(56)33(53)27(18-49)61-42/h15,22-44,49-60H,9-14,16-20H2,1-8H3/t22?,23?,24-,25?,26-,27+,28+,29+,30?,31?,32+,33+,34+,35+,36-,37-,38-,39+,40+,41+,42-,43-,44-,46+,47+,48-/m0/s1
The fungus Penicillum oxalicum can selec...
The β-glucosidase gene Tt-bgl from Therm...
The bacterium Paenibacillus sp. BG134 wa...
α-L-arabinofuranosidase is a subfamily o...
Triterpenoids with desired glycosylation...
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ginsenoside Rc
ginsenoside Rg3
ginsenoside Rd
Conditions | Yield |
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With Bacterium Leuconostoc sp. BG78; In aq. phosphate buffer; at 37 ℃; pH=7; Microbiological reaction;
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Ginsenoside Rb1
ginsenoside F2
ginsenoside Rd
Conditions | Yield |
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With recombinant β-glycosidase from Microbacterium sp. Gsoil 167, wild-type; for 24h; Enzymatic reaction;
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malonyl-ginsenoside Rb1
(3β,12β,20S)-3-[(6-O-acetyl-β-D-glucopyranosyl-(1->2)-β-D-glucopyranosyl)oxy]-20-[(β-D-glucopyranosyl)oxy]dammar-24-en-12-ol
Ginsenoside Rb1
Ginsenoside Rb3
vina-ginsenoside-R8
protopanaxadiol
ginsenoside Rg3
ginsenoside F2