• Product NameIcariin
  • CasNo. 489-32-7
  • MFC33H40O15
  • MW676.672
  • Purity
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Product Details

CasNo: 489-32-7

MF: C33H40O15

Quality Factory Supply Top Purity Icariin 489-32-7 Fast Delivery

  • Molecular Formula:C33H40O15
  • Molecular Weight:676.672
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:231-232 °C 
  • Refractive Index:1.679 
  • Boiling Point:948.5 °C at 760 mmHg 
  • PKA:5.90±0.40(Predicted) 
  • Flash Point:300.9 °C 
  • PSA:238.20000 
  • Density:1.55 g/cm3 
  • LogP:0.06790 

Icariin(Cas 489-32-7) Usage

Description

Icariin is a flavonoid glucoside that is isolated from Epimedium spp (Berberidaceae) (Shen et al., 2015) and is considered as a primary active compound of Epimedium extracts with neuroprotective and estrogen-like effects (Becher et al., 2002).

Chemical Properties

Light yellow to yellow solid

Uses

Icariin is a biologically active substance in Epimedii herba that is used for the treatment of neurologic disorders. However, a comprehensive analysis of the molecular mechanisms of icariin is lacking.

InChI:InChI=1/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1

489-32-7 Relevant articles

Antidepressant-like effect of icariin and its possible mechanism in mice

Ying Pan, Lingdong Kong, Xing Xia, Weiyun Zhang, Zhonghao Xia, Fuxin Jiang

Pharmacology Biochemistry and Behavior Volume 82, Issue 4, December 2005, Pages 686-694

Treatment of icariin for 21 consecutive days mainly reversed the above effects in the mouse FST. These results suggested that icarrin possessed potent antidepressant-like properties that were mediated via neurochemical and neuroendocrine systems.

Ep7GT, a glycosyltransferase with sugar donor flexibility from: Epimedium pseudowushanense, catalyzes the 7- O -glycosylation of baohuoside

Feng, Keping,Chen, Ridao,Xie, Kebo,Chen, Dawei,Liu, Jimei,Du, Wenyu,Yang, Lin,Dai, Jungui

supporting information, p. 8106 - 8114 (2019/09/19)

Icariin (1a), a 7-O-glycosylated flavono...

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